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IncyteCARES for PEMAZYRE is a program for residents of the United States and US territories.

What Is IncyteCARES?

Watch this short video to see how our IncyteCARES for PEMAZYRE team can help you get started with your medicine and provide as-needed support for managing various challenges along the way.

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Video: What Is IncyteCARES?

Narrator: Welcome to IncyteCARES, a support program for people prescribed an Incyte medicine.

We know that managing a health condition can be challenging. That’s why our IncyteCARES team is here—to help you get started with your medicine and to be your quick-call source when you need support along the way.

Onscreen text: Not all patients are eligible to receive all IncyteCARES services.

Narrator: Once you’re enrolled in IncyteCARES, a team member will call you. We’ll go over your insurance coverage for your medicine, so there are no surprises.

Onscreen text: Not all patients qualify. Terms and conditions apply.

Narrator: If needed, we can see if you might qualify for savings or financial assistance to help you afford your medicine. We can send your prescription to a specialty pharmacy for you, since regular pharmacies don’t carry all Incyte medicines. And we can help arrange regular deliveries. Simple, right?

From there, IncyteCARES is your on-call support team, offering guidance and easy access to resources that can help with certain challenges.

Onscreen text: Some services are not provided for all Incyte medicines.

Narrator: For instance, we can help connect you to resources for emotional support. Whether you’d like to meet with a professional counselor, find a support group, or be paired with someone who knows firsthand what you’re going through.

Have questions about your medicine or maybe a change in your insurance? Our trained representatives can provide reliable answers quickly.

Onscreen text (appears in chat bubbles from an IncyteCARES representative):
Try This
No problem
Glad to help
Just a few questions...

Narrator: If you need help with travel to medical appointments, tips for taking care of yourself, or advice for managing family, home, or work challenges, we can connect you to those types of resources as well. And so much more!

When it comes to medical advice, you have your doctor’s care. For other kinds of support, IncyteCARES may be able to help.

Ask your Healthcare Professional to enroll you, or call us today!

Connect Today! Call IncyteCARES at 1-855-452-5234, Monday through Friday, 8 AM–8 PM ET.

Onscreen copy: This video is sponsored by Incyte. Incyte and the Incyte logo are registered trademarks of Incyte.

© 2022, Incyte. MAT-INC-01813  05/22

phone support icon
Need Help?

Our IncyteCARES for PEMAZYRE team is available

Monday through Friday,
8 AM–8 PM ET

Call us at
1-855-452-5234

Video: What Is IncyteCARES?

Narrator: Welcome to IncyteCARES, a support program for people prescribed an Incyte medicine.

We know that managing a health condition can be challenging. That’s why our IncyteCARES team is here—to help you get started with your medicine and to be your quick-call source when you need support along the way.

Onscreen text: Not all patients are eligible to receive all IncyteCARES services.

Narrator: Once you’re enrolled in IncyteCARES, a team member will call you. We’ll go over your insurance coverage for your medicine, so there are no surprises.

Onscreen text: Not all patients qualify. Terms and conditions apply.

Narrator: If needed, we can see if you might qualify for savings or financial assistance to help you afford your medicine. We can send your prescription to a specialty pharmacy for you, since regular pharmacies don’t carry all Incyte medicines. And we can help arrange regular deliveries. Simple, right?

From there, IncyteCARES is your on-call support team, offering guidance and easy access to resources that can help with certain challenges.

Onscreen text: Some services are not provided for all Incyte medicines.

Narrator: For instance, we can help connect you to resources for emotional support. Whether you’d like to meet with a professional counselor, find a support group, or be paired with someone who knows firsthand what you’re going through.

Have questions about your medicine or maybe a change in your insurance? Our trained representatives can provide reliable answers quickly.

Onscreen text (appears in chat bubbles from an IncyteCARES representative):
Try This
No problem
Glad to help
Just a few questions...

Narrator: If you need help with travel to medical appointments, tips for taking care of yourself, or advice for managing family, home, or work challenges, we can connect you to those types of resources as well. And so much more!

When it comes to medical advice, you have your doctor’s care. For other kinds of support, IncyteCARES may be able to help.

Ask your Healthcare Professional to enroll you, or call us today!

Connect Today! Call IncyteCARES at 1-855-452-5234, Monday through Friday, 8 AM–8 PM ET.

Onscreen copy: This video is sponsored by Incyte. Incyte and the Incyte logo are registered trademarks of Incyte.

© 2022, Incyte. MAT-INC-01813  05/22

INDICATIONS AND USAGE

PEMAZYRE is a prescription medicine that is used to treat adults with:

  • bile duct cancer (cholangiocarcinoma) that has spread or cannot be removed by surgery:
    • who have already received a previous treatment, and
    • whose tumor has a certain type of abnormal FGFR2 gene
  • a type of blood cancer called myeloid/lymphoid neoplasms (MLNs):
    • when it has come back or did not respond to treatment, and
    • whose tumor has a certain type of abnormal FGFR1 gene

Your healthcare provider will test your cancer for certain types of abnormal FGFR1 or FGFR2 genes and make sure that PEMAZYRE is right for you.

It is not known if PEMAZYRE is safe and effective in children.

PEMAZYRE is approved based on tumor response and duration of response. There are ongoing studies to show whether PEMAZYRE can improve survival or symptoms.

IMPORTANT SAFETY INFORMATION

Before you take PEMAZYRE, tell your healthcare provider about all of your medical conditions, including if you:

  • have vision or eye problems
  • have kidney problems
  • have liver problems
  • are pregnant or plan to become pregnant. PEMAZYRE can harm your unborn baby or cause loss of your pregnancy (miscarriage). You should not become pregnant during treatment with PEMAZYRE.

    Females who can become pregnant:

    • Your healthcare provider should do a pregnancy test before you start treatment with PEMAZYRE.
    • You should use an effective method of birth control during treatment and for 1 week after your last dose of PEMAZYRE. Talk to your healthcare provider about birth control methods that may be right for you.
    • Tell your healthcare provider right away if you become pregnant or think that you may be pregnant.

    Males with female partners who can become pregnant:

    • You should use effective birth control when sexually active during treatment with PEMAZYRE and for 1 week after your last dose of PEMAZYRE.
  • are breastfeeding or plan to breastfeed. It is not known if PEMAZYRE passes into your breast milk. Do not breastfeed during treatment and for 1 week after your last dose of PEMAZYRE.

Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.

What are the possible side effects of PEMAZYRE?

PEMAZYRE may cause serious side effects, including:

  • Eye problems. Certain eye problems are common with PEMAZYRE but can also be serious. Eye problems include dry eye or inflamed eyes, inflamed cornea (front part of the eye), increased tears, and a disorder of the retina (an internal part of the eye). You will need to see an eye specialist for a complete eye exam before you begin treatment with PEMAZYRE, every 2 months for the first 6 months, and then every 3 months during treatment with PEMAZYRE.
    • You should use artificial tears or substitutes, hydrating or lubricating eye gels as needed, to help prevent or treat dry eyes.
    • Tell your healthcare provider right away if you develop any changes in your vision during treatment with PEMAZYRE, including: blurred vision, flashes of light, or see black spots. You may need to see an eye specialist right away.
  • High phosphate levels in your blood (hyperphosphatemia) and buildup of minerals in different tissues in your body. Hyperphosphatemia is common with PEMAZYRE but can also be serious. High levels of phosphate in your blood may lead to buildup of minerals such as calcium, in different tissues in your body. Your healthcare provider will check your blood phosphate levels during treatment with PEMAZYRE.
    • Your healthcare provider may prescribe changes in your diet or phosphate lowering therapy, or change, interrupt, or stop PEMAZYRE if needed.
    • Tell your healthcare provider right away if you develop any muscle cramps, or numbness or tingling around your mouth.

The most common side effects of PEMAZYRE for cholangiocarcinoma include:

  • hair loss
  • diarrhea
  • nails separate from the bed or poor formation of the nail
  • feeling tired
  • change in sense of taste
  • nausea
  • constipation
  • mouth sores
  • dry eyes
  • dry mouth
  • decrease in appetite
  • vomiting
  • joint pain
  • stomach-area (abdominal) pain
  • low phosphate in blood
  • back pain
  • dry skin

The most common side effects of PEMAZYRE for myeloid/lymphoid neoplasms (MLN) include:

  • nails separate from the bed or poor formation of the nail
  • hair loss
  • mouth sores
  • diarrhea
  • dry eyes
  • tiredness
  • anemia
  • stomach-area (abdominal) pain
  • rash
  • constipation
  • dry mouth
  • nose bleeds
  • disorder of the retina
  • pain in feet or hands
  • decrease in appetite
  • dry skin
  • indigestion
  • back pain
  • nausea
  • blurry vision
  • swelling in feet, legs, hands, or arms
  • dizziness

These are not all the possible side effects of PEMAZYRE. For more information, ask your healthcare provider or pharmacist.

Call your doctor for medical advice about side effects.

You may report side effects to FDA at 1-800-FDA-1088. You may also report side effects to Incyte Medical Information at 1-855-463-3463.

Keep PEMAZYRE and all medicines out of the reach of children.

General information about the safe and effective use of PEMAZYRE.

Medicines are sometimes prescribed for purposes other than those listed in a Patient Information leaflet. Do not use PEMAZYRE for a condition for which it is not prescribed. Do not give PEMAZYRE to other people, even if they have the same symptoms you have. It may harm them. If you would like more information, talk with your healthcare provider. You can ask your pharmacist or healthcare provider for information that is written for healthcare professionals.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

INDICATIONS AND USAGE

PEMAZYRE is a prescription medicine that is used to treat adults with:

  • bile duct cancer (cholangiocarcinoma) that has spread or cannot be removed by surgery:
    • who have already received a previous treatment, and
    • whose tumor has a certain type of abnormal FGFR2 gene
  • a type of blood cancer called myeloid/lymphoid neoplasms (MLNs):
    • when it has come back or did not respond to treatment, and
    • whose tumor has a certain type of abnormal FGFR1 gene

Your healthcare provider will test your cancer for certain types of abnormal FGFR1 or FGFR2 genes and make sure that PEMAZYRE is right for you.

It is not known if PEMAZYRE is safe and effective in children.

PEMAZYRE is approved based on tumor response and duration of response. There are ongoing studies to show whether PEMAZYRE can improve survival or symptoms.

IMPORTANT SAFETY INFORMATION

Before you take PEMAZYRE, tell your healthcare provider about all of your medical conditions, including if you:

  • have vision or eye problems
  • have kidney problems
  • have liver problems
  • are pregnant or plan to become pregnant. PEMAZYRE can harm your unborn baby or cause loss of your pregnancy (miscarriage). You should not become pregnant during treatment with PEMAZYRE.

    Females who can become pregnant:

    • Your healthcare provider should do a pregnancy test before you start treatment with PEMAZYRE.
    • You should use an effective method of birth control during treatment and for 1 week after your last dose of PEMAZYRE. Talk to your healthcare provider about birth control methods that may be right for you.
    • Tell your healthcare provider right away if you become pregnant or think that you may be pregnant.

    Males with female partners who can become pregnant:

    • You should use effective birth control when sexually active during treatment with PEMAZYRE and for 1 week after your last dose of PEMAZYRE.
  • are breastfeeding or plan to breastfeed. It is not known if PEMAZYRE passes into your breast milk. Do not breastfeed during treatment and for 1 week after your last dose of PEMAZYRE.

Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.

What are the possible side effects of PEMAZYRE?

PEMAZYRE may cause serious side effects, including:

  • Eye problems. Certain eye problems are common with PEMAZYRE but can also be serious. Eye problems include dry eye or inflamed eyes, inflamed cornea (front part of the eye), increased tears, and a disorder of the retina (an internal part of the eye). You will need to see an eye specialist for a complete eye exam before you begin treatment with PEMAZYRE, every 2 months for the first 6 months, and then every 3 months during treatment with PEMAZYRE.
    • You should use artificial tears or substitutes, hydrating or lubricating eye gels as needed, to help prevent or treat dry eyes.
    • Tell your healthcare provider right away if you develop any changes in your vision during treatment with PEMAZYRE, including: blurred vision, flashes of light, or see black spots. You may need to see an eye specialist right away.
  • High phosphate levels in your blood (hyperphosphatemia) and buildup of minerals in different tissues in your body. Hyperphosphatemia is common with PEMAZYRE but can also be serious. High levels of phosphate in your blood may lead to buildup of minerals such as calcium, in different tissues in your body. Your healthcare provider will check your blood phosphate levels during treatment with PEMAZYRE.
    • Your healthcare provider may prescribe changes in your diet or phosphate lowering therapy, or change, interrupt, or stop PEMAZYRE if needed.
    • Tell your healthcare provider right away if you develop any muscle cramps, or numbness or tingling around your mouth.

The most common side effects of PEMAZYRE for cholangiocarcinoma include:

  • hair loss
  • diarrhea
  • nails separate from the bed or poor formation of the nail
  • feeling tired
  • change in sense of taste
  • nausea
  • constipation
  • mouth sores
  • dry eyes
  • dry mouth
  • decrease in appetite
  • vomiting
  • joint pain
  • stomach-area (abdominal) pain
  • low phosphate in blood
  • back pain
  • dry skin

The most common side effects of PEMAZYRE for myeloid/lymphoid neoplasms (MLN) include:

  • nails separate from the bed or poor formation of the nail
  • hair loss
  • mouth sores
  • diarrhea
  • dry eyes
  • tiredness
  • anemia
  • stomach-area (abdominal) pain
  • rash
  • constipation
  • dry mouth
  • nose bleeds
  • disorder of the retina
  • pain in feet or hands
  • decrease in appetite
  • dry skin
  • indigestion
  • back pain
  • nausea
  • blurry vision
  • swelling in feet, legs, hands, or arms
  • dizziness

These are not all the possible side effects of PEMAZYRE. For more information, ask your healthcare provider or pharmacist.

Call your doctor for medical advice about side effects.

You may report side effects to FDA at 1-800-FDA-1088. You may also report side effects to Incyte Medical Information at 1-855-463-3463.

Keep PEMAZYRE and all medicines out of the reach of children.

General information about the safe and effective use of PEMAZYRE.

Medicines are sometimes prescribed for purposes other than those listed in a Patient Information leaflet. Do not use PEMAZYRE for a condition for which it is not prescribed. Do not give PEMAZYRE to other people, even if they have the same symptoms you have. It may harm them. If you would like more information, talk with your healthcare provider. You can ask your pharmacist or healthcare provider for information that is written for healthcare professionals.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.