Filling Your Prescription for Jakafi® (ruxolitinib)

Find out how IncyteCARES can help qualified patients fill their prescriptions for Jakafi. View the video to learn more.

The personalized assistance that IncyteCARES provides goes beyond insurance and financial assistance. The program may also be able to coordinate the delivery of Jakafi to you or your healthcare professional’s office.

Delivery coordination of Jakafi

IncyteCARES will send your prescription and any applicable copayment assistance information directly to a specialty pharmacy in the Incyte network that your insurance accepts. The specialty pharmacy will then call you to schedule shipments of Jakafi each month.

IncyteCARES Helps Coordinate Delivery of Jakafi

Why is a specialty pharmacy used to fill my prescription for Jakafi?

Jakafi is not available through local retail pharmacies. Instead, it is carried only by certain specialty pharmacies, which fill prescriptions for patients who need medicines that treat certain conditions. These drugs may require special handling and other specialty expertise.

Because Jakafi is filled through a specialty pharmacy, it is important to let both the specialty pharmacy and your retail pharmacy know about all the medicines you are taking. This includes Jakafi, other prescription medicines, and over-the-counter treatments and supplements. Taking Jakafi with certain other medicines may affect how Jakafi works.

Selected Specialty Pharmacies that Carry Jakafi

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Filling your prescription FAQs

Do I need to call IncyteCARES every month to arrange my delivery of Jakafi?

No. Typically your specialty pharmacy will contact you to see if you would like a refill of your Jakafi. However, if your specialty pharmacy does not contact you about a refill, call your specialty pharmacy or IncyteCARES.

What if my insurance changes while taking Jakafi?

If your insurance changes, call IncyteCARES to inform them of the change and they will help you understand your new benefit and whether you are now or still eligible for copay/coinsurance or other IncyteCARES programs. Your new insurance company may require a different specialty pharmacy to fill your prescription for Jakafi, in which case the new specialty pharmacy will contact you to make delivery arrangements.

Can I contact the specialty pharmacies directly in place of calling IncyteCARES?

Yes, you can send prescriptions directly to a participating Jakafi specialty pharmacy; however, IncyteCARES can offer helpful services, particularly to some patients who don't have prescription drug coverage.

Can someone call me to remind me to refill Jakafi?

Check with your specialty pharmacy. It may provide a refill reminder service.

What are the speciality pharmacies that will dispense Jakafi?

Click here to download the Specialty Pharmacy Listing.

Indications and Usage

Jakafi is a prescription medicine used to treat people with polycythemia vera who have already taken a medicine called hydroxyurea and it did not work well enough or they could not tolerate it.

Jakafi is also used to treat certain types of myelofibrosis.

Important Safety Information

Jakafi can cause serious side effects, including:

Low blood counts: Jakafi® (ruxolitinib) may cause your platelet, red blood cell, or white blood cell counts to be lowered. If you develop bleeding, stop taking Jakafi and call your healthcare provider. Your healthcare provider will perform blood tests to check your blood counts before you start Jakafi and regularly during your treatment. Your healthcare provider may change your dose of Jakafi or stop your treatment based on the results of your blood tests. Tell your healthcare provider right away if you develop or have worsening symptoms such as unusual bleeding, bruising, tiredness, shortness of breath, or a fever.

Infection: You may be at risk for developing a serious infection during treatment with Jakafi. Tell your healthcare provider if you develop any of the following symptoms of infection: chills, nausea, vomiting, aches, weakness, fever, painful skin rash or blisters.

Skin cancers: Some people who take Jakafi have developed certain types of non-melanoma skin cancers. Tell your healthcare provider if you develop any new or changing skin lesions.

Increases in cholesterol: You may have changes in your blood cholesterol levels. Your healthcare provider will do blood tests to check your cholesterol levels during your treatment with Jakafi.

The most common side effects of Jakafi include: low platelet count, low red blood cell counts, bruising, dizziness, headache.

These are not all the possible side effects of Jakafi. Ask your pharmacist or healthcare provider for more information. Tell your healthcare provider about any side effect that bothers you or that does not go away.

Before taking Jakafi, tell your healthcare provider about: all the medications, vitamins, and herbal supplements you are taking and all your medical conditions, including if you have an infection, have or had tuberculosis (TB) or have been in close contact with someone who has TB, have or had hepatitis B, have or had liver or kidney problems, are on dialysis, had skin cancer, or have any other medical condition. Take Jakafi exactly as your healthcare provider tells you. Do not change your dose or stop taking Jakafi without first talking to your healthcare provider. Do not drink grapefruit juice while on Jakafi.

Women should not take Jakafi while pregnant or planning to become pregnant, or if breast-feeding.

Please see Full Prescribing Information, which includes a more complete discussion of the risks associated with Jakafi.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit, or call 1-800-FDA-1088.

You may also report side effects to Incyte Medical Information at 1-855-463-3463.