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IncyteCARES is a program for residents of the United States and Puerto Rico.

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Get enrolled in IncyteCARES!

We offer support for eligible patients during treatment, including a program that could make your copay as little as $0.*

*Terms and conditions apply. Terms of this program may change at any time.

Ongoing Education and Support for
Jakafi® (ruxolitinib)

A key part of the IncyteCARES program is the helpful information we can provide for eligible patients and caregivers. Through our call center, we can answer questions about your condition, what you might experience during your treatment, and how to properly take Jakafi.

When you’re first prescribed Jakafi, you’ll also receive a Welcome Kit including:

  • Education about your condition
  • Information about Jakafi and research that supported its approval
  • An information card to share with your traditional pharmacy (so they’re aware of your Jakafi prescription)
  • Details about the IncyteCARES program and how to contact us

An IncyteCARES representative calls all newly enrolled patients to answer questions and see how else they can help. Depending on your underlying condition, we may also offer an ongoing series of educational mailings and occasional follow-up calls.


IncyteCARES can also connect eligible patients to resources that can help with managing your condition, having better conversations with your Healthcare Professional, and maintaining a positive outlook.

These may include:

  • Tools for tracking your symptoms and daily medicines
  • Help with finding patient or caregiver support groups
  • Sources that provide emotional, financial, and other counseling services at low or no cost
  • Information about organizations that may offer eligible patients help with transportation to medical appointments, treatment-related costs, and more


Tips for Healthy Eating and Exercising When Taking Jakafi® (ruxolitinib)

Learn about the healthy foods and exercise your body needs. Watch video >

Positive Steps for Staying on Therapy With Jakafi® (ruxolitinib)

Get tips for staying on track with your Jakafi treatment. Watch video >

"The support I get from IncyteCARES helped me keep trying when I wanted to give up. It has been a wonderful program for me."

– Billy R.

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Our IncyteCARES team is available Monday through Friday, 8 am–8 pm ET

Call us at 1-855-452-5234


Jakafi is a prescription medicine used to treat adults with polycythemia vera who have already taken a medicine called hydroxyurea and it did not work well enough or they could not tolerate it.

Jakafi is used to treat adults with certain types of myelofibrosis.

Jakafi is also used to treat adults and children 12 years of age and older with acute graft-versus-host disease (GVHD) who have taken corticosteroids and they did not work well enough.



Low blood counts: Jakafi® (ruxolitinib) may cause your platelet, red blood cell, or white blood cell counts to be lowered. If you develop bleeding, stop taking Jakafi and call your healthcare provider. Your healthcare provider will perform blood tests to check your blood counts before you start Jakafi and regularly during your treatment. Your healthcare provider may change your dose of Jakafi or stop your treatment based on the results of your blood tests. Tell your healthcare provider right away if you develop or have worsening symptoms such as unusual bleeding, bruising, tiredness, shortness of breath, or a fever.

Infection: You may be at risk for developing a serious infection during treatment with Jakafi. Tell your healthcare provider if you develop any of the following symptoms of infection: chills, nausea, vomiting, aches, weakness, fever, painful skin rash or blisters.

Skin cancers: Some people who take Jakafi have developed certain types of non-melanoma skin cancers. Tell your healthcare provider if you develop any new or changing skin lesions.

Increases in cholesterol: You may have changes in your blood cholesterol levels. Your healthcare provider will do blood tests to check your cholesterol levels during your treatment with Jakafi.

The most common side effects of Jakafi include: for certain types of MF and PV – low platelet or red blood cell counts, bruising, dizziness, headache, and diarrhea; and for acute GVHD – low platelet, red or white blood cell counts, infections, and fluid retention.

These are not all the possible side effects of Jakafi. Ask your pharmacist or healthcare provider for more information. Tell your healthcare provider about any side effect that bothers you or that does not go away.

Before taking Jakafi, tell your healthcare provider about: all the medications, vitamins, and herbal supplements you are taking and all your medical conditions, including if you have an infection, have or had tuberculosis (TB) or have been in close contact with someone who has TB, have or had hepatitis B, have or had liver or kidney problems, are on dialysis, high cholesterol or triglycerides, had skin cancer, or have any other medical condition. Take Jakafi exactly as your healthcare provider tells you. Do not change your dose or stop taking Jakafi without first talking to your healthcare provider.

Women should not take Jakafi while pregnant or planning to become pregnant. Do not breastfeed during treatment with Jakafi and for 2 weeks after the final dose.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

You may also report side effects to Incyte Medical Information at 1-855-463-3463.