Our website uses cookies which are small bits of data stored as text files on your device. We use these cookies as described in our cookie policy. You can disable or change your cookie settings at any time but parts of our site will not function correctly without them.

IncyteCARES is a program for residents of the United States and Puerto Rico.

Frequently Asked Questions for Jakafi® (ruxolitinib)

About IncyteCARES

How can I contact IncyteCARES?

Call us at 1-855-452-5234.

Our IncyteCARES team is available Monday through Friday, 8 AM–8 PM ET.

Do I have to be taking Jakafi® (ruxolitinib) to speak to an IncyteCARES representative?

No. Anyone can call IncyteCARES for general information.

Can any patient taking Jakafi enroll in the IncyteCARES program?

No. Some patients who have been prescribed Jakafi may not be eligible to enroll in the IncyteCARES program or to receive some of the services or support we offer. Contact IncyteCARES for more details and to determine if you’re eligible. Our team can be reached at 1-855-452-5234, Monday through Friday, 8 AM–8 PM ET.

How long am I enrolled in IncyteCARES?

Enrollment in the IncyteCARES program for eligible patients lasts for one year. You can re-enroll each year (we’ll remind you when it’s time!) and can continue to be part of the program for as long as you’re taking Jakafi.

How can I learn more about other patients’ experiences with IncyteCARES?

Watch our videos about real IncyteCARES patient experiences, featuring Rob, Sue, and Dan.


Do I need to call IncyteCARES every month to arrange my delivery of Jakafi?

No. Typically your specialty pharmacy will contact you each month to see if you would like a refill of your Jakafi. If you don’t receive this call, you can call your specialty pharmacy directly or contact IncyteCARES.

What if my insurance changes while taking Jakafi?

Call IncyteCARES about any insurance changes, and we can help you understand your new coverage. We can also determine if you are now, or are still, eligible for our Copay/Coinsurance Program or other financial assistance programs. Your new insurance company may require you to use a different specialty pharmacy to fill your prescription. We can help you change pharmacies if needed and coordinate your medicine delivery from the new pharmacy.

Can I contact the specialty pharmacies directly in place of calling IncyteCARES?

Yes. You can always send prescriptions directly to a participating Jakafi specialty pharmacy. Keep in mind, however, that IncyteCARES can offer helpful services, particularly if you don't have prescription drug coverage.

Can someone call me to remind me to refill Jakafi?

Check with your specialty pharmacy. It may provide a refill reminder service.

What are the specialty pharmacies that can fill a prescription for Jakafi?

Click here to download the Detailed Specialty Pharmacy List. Note that your insurance company may require you to use certain pharmacies to fill your prescription for Jakafi.


What are the enrollment criteria for the Copay/Coinsurance Program?

To qualify for the Copay/Coinsurance Program through IncyteCARES, you must meet the following criteria:

  • Have commercial or private prescription drug coverage. Patients insured under federal or state government prescription drug programs—including Medicare Part D, Medicare Advantage, Medicaid, or TRICARE—are not eligible. Patients without prescription drug coverage are also not eligible
  • Be a resident of the United States or Puerto Rico
  • Have a valid prescription for Jakafi for an FDA-approved use

Read complete terms and conditions here.

For more information, call IncyteCARES at 1-855-452-5234.

How do I enroll for copay/coinsurance assistance through IncyteCARES?

You can ask your prescribing Healthcare Professional, Specialty Pharmacist, or IncyteCARES to check your eligibility and enroll you in the program.

Read complete terms and conditions here.

For more information, call IncyteCARES at 1-855-452-5234.

How long does it take to find out if I’m approved for the IncyteCARES Copay/Coinsurance Program?

Once your Healthcare Professional submits your completed enrollment form, or you answer a few questions on a call with IncyteCARES, eligibility is determined right away. A program member number is typically issued immediately. Either you or IncyteCARES can share this member number with your specialty pharmacy, so it can be applied to your prescription for Jakafi.

Once I’m approved for the Copay/Coinsurance Program, do I ever have to re-enroll?

No. Your enrollment in the Copay/Coinsurance Program will automatically renew each year. You do not need to re-enroll. You should, however, contact IncyteCARES if your prescription insurance plan changes, so we can update your information.

What are the eligibility criteria for the Patient Assistance Program through IncyteCARES?

The Patient Assistance Program (PAP) program helps eligible patients who do not have prescription drug insurance and have trouble affording their copay for Jakafi. No purchase contingencies or other obligations apply.

To qualify, you must:*

  • Be confirmed as eligible for and enrolled in IncyteCARES for Jakafi
  • Be a resident of the United States or Puerto Rico
  • Have a valid prescription for Jakafi for an FDA-approved use or a clinical compendia-listed use approved for coverage by Medicare
  • Meet one of these criteria:
    • Uninsured with no coverage
      • Meet certain household size and annual income criteria, including but not limited to earning less than $125,000 per year or less than 600% of the Federal Poverty Level (FPL), whichever amount is higher
    • Underinsured
      • Commercially insured patients who have exhausted their benefit and have an inability to afford their medication or copay
      • Meet certain household size and income criteria, including but not limited to earning less than 600% of the FPL
      • Medicare Part D patients may be eligible by meeting additional criteria and program requirements, including but not limited to earning less than 600% of the FPL

For more information, call IncyteCARES at 1-855-452-5234.

*Terms and conditions apply. Terms of this program may change at any time.

How long does it take to find out if a patient has been approved for the PAP?

Conditional approval for the PAP is provided in 1 to 2 business days after we receive your completed enrollment form. That means you’re approved for a supply of free medicine for 90 days. In the meantime, you must send us proof of your current household income. Once your income eligibility is confirmed, you’ll be fully approved for the PAP.

What are acceptable documents to prove my income eligibility for the PAP?

You must document your current household income by submitting one of the following: your most recent federal income tax return, your most recent W-2 earnings statement from your employer, or one month of recent pay stubs.

How does conditional approval work for the PAP?

Once we receive your completed PAP enrollment form, you will be given "conditional approval" for the program. This means you are temporarily approved for the program, for up to 90 days, until we can review and approve the financial information (household size and current annual income) you must send to IncyteCARES.

Once I’m approved for PAP, how long does it last? Do I need to reapply each year?

Yes. If you are enrolled in Medicare but do not have Medicare Part D prescription drug coverage, you are required to reapply for PAP each calendar year. If you are not uninsured and not Medicare-eligible, you are required to reapply each year after your original approval date.


How long does it take to find out about my insurance coverage for Jakafi?

Once we receive your insurance information, we can research your coverage for Jakafi right away. In most cases, we’ll call you with this information within 2 business days. If there is a delay, we’ll notify you and/or your Healthcare Professional within that time frame.

How often does my insurance coverage need to be verified through IncyteCARES?

Your enrollment in the IncyteCARES program lasts for one year. That means you must re-enroll annually by submitting a new enrollment form. At that time, we also have to reconfirm your insurance coverage for Jakafi.

What if my insurance changes?

Please contact IncyteCARES if your insurance coverage changes or is lost or if you have a life-changing event such as a job loss or other change in household income. We can determine any changes in your coverage for Jakafi or your out-of-pocket costs. We can also find out if your specialty pharmacy is still within network for your insurer and can communicate any changes to them. If you need to change specialty pharmacies, we can help with that as well.

Telephone icon


Our IncyteCARES team is available Monday through Friday, 8 am–8 pm ET

Call us at 1-855-452-5234


Jakafi is a prescription medicine used to treat adults with polycythemia vera who have already taken a medicine called hydroxyurea and it did not work well enough or they could not tolerate it.

Jakafi is used to treat adults with certain types of myelofibrosis.

Jakafi is also used to treat adults and children 12 years of age and older with acute graft-versus-host disease (GVHD) who have taken corticosteroids and they did not work well enough.



Low blood counts: Jakafi® (ruxolitinib) may cause your platelet, red blood cell, or white blood cell counts to be lowered. If you develop bleeding, stop taking Jakafi and call your healthcare provider. Your healthcare provider will perform blood tests to check your blood counts before you start Jakafi and regularly during your treatment. Your healthcare provider may change your dose of Jakafi or stop your treatment based on the results of your blood tests. Tell your healthcare provider right away if you develop or have worsening symptoms such as unusual bleeding, bruising, tiredness, shortness of breath, or a fever.

Infection: You may be at risk for developing a serious infection during treatment with Jakafi. Tell your healthcare provider if you develop any of the following symptoms of infection: chills, nausea, vomiting, aches, weakness, fever, painful skin rash or blisters.

Skin cancers: Some people who take Jakafi have developed certain types of non-melanoma skin cancers. Tell your healthcare provider if you develop any new or changing skin lesions.

Increases in cholesterol: You may have changes in your blood cholesterol levels. Your healthcare provider will do blood tests to check your cholesterol levels during your treatment with Jakafi.

The most common side effects of Jakafi include: for certain types of MF and PV – low platelet or red blood cell counts, bruising, dizziness, headache, and diarrhea; and for acute GVHD – low platelet, red or white blood cell counts, infections, and fluid retention.

These are not all the possible side effects of Jakafi. Ask your pharmacist or healthcare provider for more information. Tell your healthcare provider about any side effect that bothers you or that does not go away.

Before taking Jakafi, tell your healthcare provider about: all the medications, vitamins, and herbal supplements you are taking and all your medical conditions, including if you have an infection, have or had tuberculosis (TB) or have been in close contact with someone who has TB, have or had hepatitis B, have or had liver or kidney problems, are on dialysis, have high cholesterol or triglycerides, had skin cancer, or have any other medical condition. Take Jakafi exactly as your healthcare provider tells you. Do not change your dose or stop taking Jakafi without first talking to your healthcare provider.

Women should not take Jakafi while pregnant or planning to become pregnant. Do not breastfeed during treatment with Jakafi and for 2 weeks after the final dose.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

You may also report side effects to Incyte Medical Information at 1-855-463-3463.