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IncyteCARES is a program for residents of the United States and Puerto Rico.

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Get enrolled in IncyteCARES!

We offer support for eligible patients during treatment, including a program that could make your copay as little as $0.*

*Terms and conditions apply. Terms of this program may change at any time.

Filling Your Prescription for
Jakafi® (ruxolitinib)

Just starting treatment with Jakafi? Need to change pharmacies? IncyteCARES can arrange to have your prescription filled and delivered by an approved specialty pharmacy. You can choose to have your prescription shipped to you or to your Healthcare Professional’s office. Once you enroll in IncyteCARES, we will call you to offer this service, or you can contact IncyteCARES yourself to request it.


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IncyteCARES receives your prescription from your Healthcare Professional

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We identify a specialty pharmacy that works with your insurance

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We send the specialty pharmacy your prescription and details of any IncyteCARES financial assistance program you’re enrolled in

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The specialty pharmacy calls you to schedule your shipment of Jakafi each month

You can also send your prescription directly to one of the specialty pharmacies in our network, if you prefer.


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Specialty pharmacies usually handle medicines that require more care or that are prescribed for less common or more complex health conditions. Jakafi is one of many medicines available only through specialty pharmacies. You can’t fill your prescription for it at a traditional local pharmacy. Remember: It’s important to give every pharmacy you use a complete list of all medicines (prescription and over-the-counter), vitamins, and supplements you take on a regular basis—so the pharmacy can make sure you’re not at risk for any drug interactions.

"They (the IncyteCARES team) have been wonderful and efficient and effective. I could not say enough good things."

– Ron C.

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Our IncyteCARES team is available Monday through Friday, 8 am–8 pm ET

Call us at 1-855-452-5234


Jakafi is a prescription medicine used to treat adults with polycythemia vera who have already taken a medicine called hydroxyurea and it did not work well enough or they could not tolerate it.

Jakafi is used to treat adults with certain types of myelofibrosis.

Jakafi is also used to treat adults and children 12 years of age and older with acute graft-versus-host disease (GVHD) who have taken corticosteroids and they did not work well enough.



Low blood counts: Jakafi® (ruxolitinib) may cause your platelet, red blood cell, or white blood cell counts to be lowered. If you develop bleeding, stop taking Jakafi and call your healthcare provider. Your healthcare provider will perform blood tests to check your blood counts before you start Jakafi and regularly during your treatment. Your healthcare provider may change your dose of Jakafi or stop your treatment based on the results of your blood tests. Tell your healthcare provider right away if you develop or have worsening symptoms such as unusual bleeding, bruising, tiredness, shortness of breath, or a fever.

Infection: You may be at risk for developing a serious infection during treatment with Jakafi. Tell your healthcare provider if you develop any of the following symptoms of infection: chills, nausea, vomiting, aches, weakness, fever, painful skin rash or blisters.

Skin cancers: Some people who take Jakafi have developed certain types of non-melanoma skin cancers. Tell your healthcare provider if you develop any new or changing skin lesions.

Increases in cholesterol: You may have changes in your blood cholesterol levels. Your healthcare provider will do blood tests to check your cholesterol levels during your treatment with Jakafi.

The most common side effects of Jakafi include: for certain types of MF and PV – low platelet or red blood cell counts, bruising, dizziness, headache, and diarrhea; and for acute GVHD – low platelet, red or white blood cell counts, infections, and fluid retention.

These are not all the possible side effects of Jakafi. Ask your pharmacist or healthcare provider for more information. Tell your healthcare provider about any side effect that bothers you or that does not go away.

Before taking Jakafi, tell your healthcare provider about: all the medications, vitamins, and herbal supplements you are taking and all your medical conditions, including if you have an infection, have or had tuberculosis (TB) or have been in close contact with someone who has TB, have or had hepatitis B, have or had liver or kidney problems, are on dialysis, have high cholesterol or triglycerides, had skin cancer, or have any other medical condition. Take Jakafi exactly as your healthcare provider tells you. Do not change your dose or stop taking Jakafi without first talking to your healthcare provider.

Women should not take Jakafi while pregnant or planning to become pregnant. Do not breastfeed during treatment with Jakafi and for 2 weeks after the final dose.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

You may also report side effects to Incyte Medical Information at 1-855-463-3463.